MovDisordV3, Main, Exploration, bibRecord, 000262

Distinctive distribution of phospho-alpha-synuclein in dermal nerves in multiple system atrophy.

Identifieur interne : 000262 ( Main/Exploration ); précédent : 000261; suivant : 000263

Distinctive distribution of phospho-alpha-synuclein in dermal nerves in multiple system atrophy.

Auteurs : Kathrin Doppler [Allemagne] ; Jessica Weis [Allemagne] ; Katharina Karl [Allemagne] ; Sönke Ebert [Allemagne] ; Jens Ebentheuer [Allemagne] ; Claudia Trenkwalder [Allemagne] ; Stephan Klebe [Allemagne] ; Jens Volkmann [Allemagne] ; Claudia Sommer [Allemagne]

Source :

Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2015.

RBID : pubmed:26175301

Abstract

MSA is characterized by deposition of alpha-synuclein (α-Syn) in oligodendrocytes and central nervous system (CNS) neurons. After recently detecting phospho-α-Syn (p-α-Syn) in dermal nerve fibers of patients with Parkinson's disease (PD), we assessed skin biopsies from patients with MSA to evaluate its potential role as a biomarker.

DOI: 10.1002/mds.26293
PubMed: 26175301

Affiliations:

Le document en format XML

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<author><name sortKey="Weis, Jessica" sort="Weis, Jessica" uniqKey="Weis J" first="Jessica" last="Weis">Jessica Weis</name>
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<author><name sortKey="Volkmann, Jens" sort="Volkmann, Jens" uniqKey="Volkmann J" first="Jens" last="Volkmann">Jens Volkmann</name>
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<author><name sortKey="Ebentheuer, Jens" sort="Ebentheuer, Jens" uniqKey="Ebentheuer J" first="Jens" last="Ebentheuer">Jens Ebentheuer</name>
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<author><name sortKey="Trenkwalder, Claudia" sort="Trenkwalder, Claudia" uniqKey="Trenkwalder C" first="Claudia" last="Trenkwalder">Claudia Trenkwalder</name>
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<front><div type="abstract" xml:lang="en">MSA is characterized by deposition of alpha-synuclein (α-Syn) in oligodendrocytes and central nervous system (CNS) neurons. After recently detecting phospho-α-Syn (p-α-Syn) in dermal nerve fibers of patients with Parkinson's disease (PD), we assessed skin biopsies from patients with MSA to evaluate its potential role as a biomarker.</div>
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<name sortKey="Ebentheuer, Jens" sort="Ebentheuer, Jens" uniqKey="Ebentheuer J" first="Jens" last="Ebentheuer">Jens Ebentheuer</name>
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<name sortKey="Klebe, Stephan" sort="Klebe, Stephan" uniqKey="Klebe S" first="Stephan" last="Klebe">Stephan Klebe</name>
<name sortKey="Sommer, Claudia" sort="Sommer, Claudia" uniqKey="Sommer C" first="Claudia" last="Sommer">Claudia Sommer</name>
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Movement Disorders (revue)

Distinctive distribution of phospho-alpha-synuclein in dermal nerves in multiple system atrophy.

Distinctive distribution of phospho-alpha-synuclein in dermal nerves in multiple system atrophy.

Source :

Abstract

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